{"id":10689,"date":"2018-06-26T00:08:00","date_gmt":"2018-06-26T03:08:00","guid":{"rendered":"https:\/\/nutritotal.com.br\/pro?p=10689"},"modified":"2023-05-31T15:17:43","modified_gmt":"2023-05-31T18:17:43","slug":"existe-relaa-a-o-entre-saaode-intestinal-e-hipercolesterolemia","status":"publish","type":"post","link":"https:\/\/nutritotal.com.br\/pro\/existe-relaa-a-o-entre-saaode-intestinal-e-hipercolesterolemia\/","title":{"rendered":"Existe rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia?"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"img-responsive\" style=\"float: left;margin: 0 .5em 0 0\" role=\"presentation\" src=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2018\/06\/colesterol.jpg\" alt=\"\" width=\"300\" height=\"218\" \/><\/p>\n<p>A microbiota intestinal participa da regula\u00e7\u00e3o da absor\u00e7\u00e3o de lip\u00eddios no intestino, o que estabelece rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia.<\/p>\n<p>Existem diferen\u00e7as entre a composi\u00e7\u00e3o da microbiota intestinal de indiv\u00edduos saud\u00e1veis e aqueles com colesterol alto. A diferen\u00e7a \u00e9 atribu\u00edda \u00e0s \u00a0altera\u00e7\u00f5es metab\u00f3licas e uso de medicamentos que reduzem o colesterol. Khan e colaboradores(2018) identificaram que indiv\u00edduos com hipercolesterolemia sem tratamento e aqueles em tratamento com atorvastatina possuem menor diversidade microbiana, maior quantidade de bact\u00e9rias inflamat\u00f3rias (<i>Faecalibacteriumprausnitzii, Akkermansia muciniphila<\/i> e <i>Oscillospira<\/i>),e maior quantidade de bact\u00e9rias relacionadas \u00e0 aterosclerose (g\u00eanero <i>Collinsella<\/i>).<\/p>\n<p>O uso de probi\u00f3ticos pode auxiliar na redu\u00e7\u00e3o do colesterol por modular a absor\u00e7\u00e3o de colesterol nas superf\u00edcies celulares, sua assimila\u00e7\u00e3o em membranas celulares, a atividade da redutas e do colesterol, e a desconjuga\u00e7\u00e3o de \u00e1cidos biliares via hidr\u00f3lise de sal biliar, oque pode aumentar a excre\u00e7\u00e3o de colesterol pelas fezes e a utiliza\u00e7\u00e3o de colesterol circulante na s\u00edntese de novos \u00e1cidos biliares. Os probi\u00f3ticos lactobacilos das esp\u00e9cies <i>L.acidophilus, L.plantarum, L.fermentum <\/i>e<i> L.gasseri<\/i>t\u00eam sido testados na melhora do perfil lip\u00eddico. Costabile e colaboradores(2017) observaram que suplementa\u00e7\u00e3o de 2&#215;10<sup>9<\/sup> UFC de <i>L. plantarum<\/i> durante 12 semanas se associou com redu\u00e7\u00e3o de \u00a0colesterol total e triglic\u00e9rides e aumento de HDL-c.<\/p>\n<p>Neste sentido, o sequenciamento gen\u00e9tico do microbioma intestinal permite avaliar a associa\u00e7\u00e3o entre disbiose e hipercolesterolemia, e permite a melhor indica\u00e7\u00e3o de probi\u00f3ticos para auxiliar na preven\u00e7\u00e3o ou controle dessa altera\u00e7\u00e3o metab\u00f3lica.<\/p>\n<p><strong>Leia mais sobre o assunto na S\u00e9rie Microbioma:<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/o-que-a-simbiose-e-disbiose\/\" target=\"_blank\" rel=\"noopener\">O que \u00e9 simbiose e disbiose?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/como-a-disbiose-intestinal-pode-contribuir-para-o-surgimento-de-doena-as\/\" target=\"_blank\" rel=\"noopener\">Como a disbiose intestinal pode contribuir para o surgimento de doen\u00e7as?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/quais-sa-o-os-fatores-que-afetam-o-microbioma-intestinal\/\" target=\"_blank\" rel=\"noopener\">Quais s\u00e3o os fatores que afetam o microbioma intestinal?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/a-possa-vel-avaliar-o-microbioma-humano\/\" target=\"_blank\" rel=\"noopener\">\u00c9 poss\u00edvel avaliar o microbioma humano?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/qual-a-a-influencia-da-dieta-no-microbioma-intestinal\/\" target=\"_blank\" rel=\"noopener\">Qual \u00e9 a influencia da dieta no microbioma intestinal?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/quais-sa-o-as-principais-bacta-rias-do-microbioma-intestinal\/\" target=\"_blank\" rel=\"noopener\">Quais s\u00e3o as principais bact\u00e9rias do microbioma intestinal?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/quais-espa-cies-microbianas-intestinais-sa-o-fundamentais-para-o-equila-brio-da-microbiota\/\" target=\"_blank\" rel=\"noopener\">Quais esp\u00e9cies microbianas intestinais s\u00e3o fundamentais para o equil\u00edbrio da microbiota?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/existe-relaa-a-o-causal-entre-alteraa-a-o-da-microbiota-intestinal-e-obesidade\/\" target=\"_blank\" rel=\"noopener\">Existe rela\u00e7\u00e3o causal entre altera\u00e7\u00e3o da microbiota intestinal e obesidade?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/existe-relaa-a-o-causal-entre-alteraa-a-o-da-microbiota-intestinal-e-diabetes\/\" target=\"_blank\" rel=\"noopener\">Existe rela\u00e7\u00e3o causal entre altera\u00e7\u00e3o da microbiota intestinal e diabetes?<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A microbiota intestinal participa da regula\u00e7\u00e3o da absor\u00e7\u00e3o de lip\u00eddios no intestino, o que estabelece rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia. Existem diferen\u00e7as entre a composi\u00e7\u00e3o da microbiota intestinal de indiv\u00edduos saud\u00e1veis e aqueles com colesterol alto. A diferen\u00e7a \u00e9 atribu\u00edda \u00e0s \u00a0altera\u00e7\u00f5es metab\u00f3licas e uso de medicamentos que reduzem o colesterol. Khan e colaboradores(2018) [&hellip;]<\/p>\n","protected":false},"author":45,"featured_media":10688,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"divisao":[3393,2186,2193],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Existe rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia? - Nutritotal PRO<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nutritotal.com.br\/pro\/existe-relaa-a-o-entre-saaode-intestinal-e-hipercolesterolemia\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Existe rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia? - Nutritotal PRO\" \/>\n<meta property=\"og:description\" content=\"A microbiota intestinal participa da regula\u00e7\u00e3o da absor\u00e7\u00e3o de lip\u00eddios no intestino, o que estabelece rela\u00e7\u00e3o entre sa\u00fade intestinal e hipercolesterolemia. Existem diferen\u00e7as entre a composi\u00e7\u00e3o da microbiota intestinal de indiv\u00edduos saud\u00e1veis e aqueles com colesterol alto. A diferen\u00e7a \u00e9 atribu\u00edda \u00e0s \u00a0altera\u00e7\u00f5es metab\u00f3licas e uso de medicamentos que reduzem o colesterol. 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