{"id":53019,"date":"2022-02-21T11:02:48","date_gmt":"2022-02-21T14:02:48","guid":{"rendered":"https:\/\/nutritotal.com.br\/pro\/?p=53019"},"modified":"2023-05-31T13:48:11","modified_gmt":"2023-05-31T16:48:11","slug":"probioticos-tratamento-covid-19","status":"publish","type":"post","link":"https:\/\/nutritotal.com.br\/pro\/probioticos-tratamento-covid-19\/","title":{"rendered":"Suplementa\u00e7\u00e3o de probi\u00f3ticos e tratamento ambulatorial de covid 19"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_75 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Conte\u00fado<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabela de conte\u00fado\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-tratamento-covid-19\/#Probioticos_e_covid-19_como_o_estudo_foi_conduzido\" >Probi\u00f3ticos e covid-19, como o estudo foi conduzido?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-tratamento-covid-19\/#Beneficios_da_suplementacao_de_probioticos\" >Benef\u00edcios da suplementa\u00e7\u00e3o de probi\u00f3ticos<\/a><\/li><\/ul><\/nav><\/div>\n<div id=\"attachment_53020\" style=\"width: 1150px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-53020\" class=\"wp-image-53020 size-full\" src=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/02\/COVID-19_site.png\" alt=\"probi\u00f3ticos tratamento covid-19\" width=\"1140\" height=\"460\" srcset=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/02\/COVID-19_site.png 1140w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/02\/COVID-19_site-300x121.png 300w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/02\/COVID-19_site-1024x413.png 1024w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/02\/COVID-19_site-768x310.png 768w\" sizes=\"(max-width: 1140px) 100vw, 1140px\" \/><p id=\"caption-attachment-53020\" class=\"wp-caption-text\">Fonte: Shutterstock<\/p><\/div>\n<p>A infec\u00e7\u00e3o causada por SARS-CoV2, covid -19, pode variar de assintom\u00e1tica \u00e0 morte, mas a maioria dos pacientes sintom\u00e1ticos geralmente apresenta sintomas leves a moderados, que incluem tosse seca, febre, falta de ar, dores no corpo, dor de cabe\u00e7a, fadiga, diarreia e anosmia, entre outros.<\/p>\n<p>Normalmente, discute-se muito a <a href=\"https:\/\/nutritotal.com.br\/pro\/tv-nutritotal\/terapia-nutricional-no-covid-19-o-que-aprendemos\/\">terapia aplicada em casos de graves da Covid-19<\/a>, mas com o aumento dos casos ambulatoriais, tem aumentado tamb\u00e9m a procura por alternativas de tratamento para pacientes com sintomas leves a moderados.<\/p>\n<p>Considerando estudos com probi\u00f3ticos orais, que sugerem que esses podem ter um papel em infec\u00e7\u00f5es respirat\u00f3rias, como resfriado e gripe, al\u00e9m da rela\u00e7\u00e3o conhecida entre <a href=\"https:\/\/nutritotal.com.br\/pro\/tv-nutritotal\/cobertura-ganepao-2021-prebioticos-probioticos-simbioticos-e-imunidade\/\">microbiota e sistema imunol\u00f3gico<\/a>, este estudo teve como objetivo testar a efic\u00e1cia e seguran\u00e7a de uma\u00a0f\u00f3rmula probi\u00f3tica contendo <sup>\u00a0<\/sup><em>Lactiplantibacillus plantarum<\/em>\u00a0KABP022, KABP023 e KABP033 e\u00a0<em>Pediococcus acidilactici<\/em>\u00a0cepa KABP021, em pacientes ambulatoriais Covid19 sintom\u00e1ticos.<\/p>\n<p>&nbsp;<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Probioticos_e_covid-19_como_o_estudo_foi_conduzido\"><\/span><strong>Probi\u00f3ticos e covid-19, como o estudo foi conduzido? <\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Este estudo foi randomizado, placebo-controlado e quadruplo cego. Foram selecionados 300 adultos com COVID-19 (PCR), n\u00e3o hospitalizados, sendo que 42% apresentavam fatores de risco para maior gravidade da doen\u00e7a.<\/p>\n<p>Esses pacientes foram randomizados em 2 grupos: placebo vs tratamento, sendo que o grupo de tratamento recebeu suplementa\u00e7\u00e3o dos probi\u00f3ticos citados por 30 dias.<\/p>\n<p>Os pesquisadores avaliaram os seguintes desfechos: i) propor\u00e7\u00e3o de pacientes em completa remiss\u00e3o sintom\u00e1tica e viral;\u00a0ii) propor\u00e7\u00e3o que evoluiu para doen\u00e7a moderada ou grave com interna\u00e7\u00e3o ou \u00f3bito;\u00a0e iii) dias em Unidade de Terapia Intensiva (UTI).<\/p>\n<p>&nbsp;<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Beneficios_da_suplementacao_de_probioticos\"><\/span><strong>Benef\u00edcios da suplementa\u00e7\u00e3o de probi\u00f3ticos <\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>O grupo que recebeu probi\u00f3ticos reduziu significativamente: dias de febre, tosse, dor de cabe\u00e7a, dores no corpo, dispn\u00e9ia, sintomas gastrintestinais. Al\u00e9m disso, foi associado a menor carga viral nasofar\u00edngea e menor infiltrado pulmonar nos dias 15 e 30 em compara\u00e7\u00e3o com placebo.<\/p>\n<p>Laboratorialmente, o grupo que recebeu probi\u00f3ticos apresentou n\u00edveis s\u00e9ricos mais elevados de anticorpos IgG e IgM e redu\u00e7\u00e3o de marcadores inflamat\u00f3rios e tromb\u00f3ticos PCR e D-d\u00edmero.<\/p>\n<p>Os autores conclu\u00edram que essa suplementa\u00e7\u00e3o probi\u00f3tica foi associada ao aumento significativo na remiss\u00e3o viral e sintom\u00e1tica de pacientes n\u00e3o hospitalizados com\u00a0 Covid19.<\/p>\n<p>&nbsp;<\/p>\n<p><iframe loading=\"lazy\" title=\"Suplementa\u00e7\u00e3o de probi\u00f3ticos e tratamento ambulatorial de covid 19\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/05rYNw4sG70?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p>Veja tamb\u00e9m:\u00a0 <a href=\"https:\/\/nutritotal.com.br\/pro\/covid-longo-evolucao-da-desnutricao-e-perda-de-forca-muscular\/\">Covid longo: evolu\u00e7\u00e3o da desnutri\u00e7\u00e3o e perda de for\u00e7a muscular<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Refer\u00eancia<\/strong><\/p>\n<p>Guti\u00e9rrez-Castrell\u00f3n P, Gandara-Mart\u00ed T, Abreu Y Abreu AT, et al. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8757475\/\">Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial<\/a>. Gut Microbes. 2022;14(1):2018899. doi:10.1080\/19490976.2021.2018899<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A infec\u00e7\u00e3o causada por SARS-CoV2, covid -19, pode variar de assintom\u00e1tica \u00e0 morte, mas a maioria dos pacientes sintom\u00e1ticos geralmente apresenta sintomas leves a moderados, que incluem tosse seca, febre, falta de ar, dores no corpo, dor de cabe\u00e7a, fadiga, diarreia e anosmia, entre outros. Normalmente, discute-se muito a terapia aplicada em casos de graves [&hellip;]<\/p>\n","protected":false},"author":115166,"featured_media":53021,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1399],"tags":[427,1506,99],"divisao":[2185,2186,2193],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Suplementa\u00e7\u00e3o de probi\u00f3ticos e tratamento ambulatorial de covid 19 - Nutritotal PRO<\/title>\n<meta name=\"description\" content=\"Pesquisadores identificaram que a utiliza\u00e7\u00e3o de algumas cepas de probi\u00f3ticos favoreceu o tratamento de covid-19 leve a moderada.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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