{"id":57079,"date":"2023-02-14T14:29:56","date_gmt":"2023-02-14T17:29:56","guid":{"rendered":"https:\/\/nutritotal.com.br\/pro\/?p=57079"},"modified":"2023-05-31T10:58:11","modified_gmt":"2023-05-31T13:58:11","slug":"probioticos-e-cancer-colorretal","status":"publish","type":"post","link":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/","title":{"rendered":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_75 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Conte\u00fado<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabela de conte\u00fado\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#Metodologia_foram_100_pacientes_investigados\" >Metodologia: foram 100 pacientes investigados<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#As_complicacoes_gastrointestinais_diminuiram\" >As complica\u00e7\u00f5es gastrointestinais diminu\u00edram<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#Os_probioticos_restauraram_a_microbiota_intestinal_alterada\" >Os probi\u00f3ticos restauraram a microbiota intestinal alterada<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#A_producao_de_AGCC_aumentou\" >A produ\u00e7\u00e3o de AGCC aumentou<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#Conclusao\" >Conclus\u00e3o<\/a><\/li><\/ul><\/nav><\/div>\n<p>O <strong>c\u00e2ncer colorretal<\/strong> \u00e9 um dos tumores malignos mais comuns na popula\u00e7\u00e3o mundial. Dentre as op\u00e7\u00f5es de tratamento, a quimioterapia pode trazer efeitos positivos. Por\u00e9m, as complica\u00e7\u00f5es tamb\u00e9m s\u00e3o comuns, tais como a disbiose intestinal, a diarreia e a dor abdominal. Neste sentido, seriam os <strong>probi\u00f3ticos<\/strong> uma op\u00e7\u00e3o eficaz para o tratamento auxiliar?<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-57082 size-full\" src=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal.png\" alt=\"a\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais\" width=\"1150\" height=\"460\" srcset=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal.png 1150w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-300x120.png 300w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-1024x410.png 1024w, https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-768x307.png 768w\" sizes=\"(max-width: 1150px) 100vw, 1150px\" \/><\/p>\n<p>Buscando responder esta pergunta, cientistas chineses buscaram investigar os prov\u00e1veis benef\u00edcios dos <a href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-intestino-e-saude-existe-relacao\/\">probi\u00f3ticos<\/a> na atenua\u00e7\u00e3o dos efeitos adversos em pacientes com <a href=\"https:\/\/nutritotal.com.br\/pro\/consumo-de-carne-vermelha-e-processada-aumenta-risco-de-cancer-colorretal\/\">c\u00e2ncer colorretal<\/a>. Ser\u00e1 que os resultados foram satisfat\u00f3rios? Continue lendo para descobrir.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"Metodologia_foram_100_pacientes_investigados\"><\/span><strong>Metodologia: foram 100 pacientes investigados<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Neste estudo prospectivo randomizado, foram recrutados 100 pacientes com c\u00e2ncer colorretal, com necessidade de ressec\u00e7\u00e3o cir\u00fargica e quimioterapia. Os participantes foram divididos aleatoriamente em um grupo de interven\u00e7\u00e3o (\u201cProbio\u201d) e um grupo placebo.<\/p>\n<p>Os pacientes do grupo Probio foram instru\u00eddos a consumir <a href=\"https:\/\/nutritotal.com.br\/pro\/como-o-uso-de-probioticos-pode-melhorar-o-desconforto-intestinal\/\">comprimidos probi\u00f3ticos<\/a> por via oral, tr\u00eas vezes ao dia. Cada comprimido pesava 0,5 g e continha mais de 0,5 \u00d7 10<sup>6<\/sup> CFU de <em>B. infants<\/em>,<em> L. acidophilus<\/em>, e <em>E. faecalis<\/em>; e mais de 0,5 \u00d7 10<sup>5<\/sup> CFU de<em> B. cereus<\/em>. Ao todo, a interven\u00e7\u00e3o durou seis semanas.<\/p>\n<p>Complica\u00e7\u00f5es gastrointestinais foram registrados durante a quimioterapia, tais como n\u00e1usea, refluxo, dor abdominal, distens\u00e3o abdominal, constipa\u00e7\u00e3o e diarreia.<\/p>\n<p>Al\u00e9m disso, amostras fecais foram coletadas para sequenciamento do rRNA 16S, e an\u00e1lise de \u00e1cidos graxos de cadeia curta (AGCC).<\/p>\n<h1><span class=\"ez-toc-section\" id=\"As_complicacoes_gastrointestinais_diminuiram\"><\/span><strong>As complica\u00e7\u00f5es gastrointestinais diminu\u00edram<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Ap\u00f3s a an\u00e1lise dos resultados, os pesquisadores constataram que n\u00e3o houve diferen\u00e7as significativas nos exames sangu\u00edneos dos dois grupos, indicando que os probi\u00f3ticos n\u00e3o alteraram a efic\u00e1cia da quimioterapia.<\/p>\n<p>Por outro lado, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais induzidas pelo tratamento, particularmente a <a href=\"https:\/\/nutritotal.com.br\/pro\/material\/diretriz-de-cuidados-ao-paciente-oncologico-com-diarreia\/\">diarreia<\/a> \u2014 que foi menor do que no grupo placebo.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"Os_probioticos_restauraram_a_microbiota_intestinal_alterada\"><\/span><strong>Os probi\u00f3ticos restauraram a microbiota intestinal alterada<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Foi demonstrado que o tratamento quimioter\u00e1pico causou mudan\u00e7as significativas na flora intestinal dos pacientes, dentre elas:<\/p>\n<ul>\n<li>Redu\u00e7\u00e3o da diversidade bacteriana;<\/li>\n<li>Diminui\u00e7\u00e3o dos filos Firmicutes e Fusobacteria;<\/li>\n<li>Aumento dos filos Bacteroidetes, Proteobacteria e Verrucomicrobia.<\/li>\n<\/ul>\n<p>No entanto, em compara\u00e7\u00e3o com o grupo placebo, a microbiota intestinal dos pacientes no grupo \u201cProbio\u201d foi enriquecida com os g\u00eaneros Blautia, Haemohilus, Alistipes, Gemmiger e Clostridium; e as fam\u00edlias Rikenellaceae e Clostridiaceae.<\/p>\n<p>Portanto, esses resultados indicaram que a administra\u00e7\u00e3o de probi\u00f3ticos pode remodelar as popula\u00e7\u00f5es bacterianas intestinais perturbadas pelo tratamento oncol\u00f3gico.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"A_producao_de_AGCC_aumentou\"><\/span><strong>A produ\u00e7\u00e3o de AGCC aumentou<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Al\u00e9m das mudan\u00e7as na microbiota, o tratamento qu\u00edmico para o c\u00e2ncer colorretal tamb\u00e9m diminiui os n\u00edveis dos principais \u00e1cidos graxos de cadeia curta (AGCC).<\/p>\n<p>Por\u00e9m, a ingest\u00e3o de <a href=\"https:\/\/nutritotal.com.br\/pro\/como-obter-probia-ticos-da-alimentaa-a-o\/\">probi\u00f3ticos<\/a> recuperou esses n\u00edveis, aumentando a produ\u00e7\u00e3o de acetato, butirato e propionato. Sugere-se que a recupera\u00e7\u00e3o da popula\u00e7\u00e3o bacteriana tenha recuperado a produ\u00e7\u00e3o destes AGCC.<\/p>\n<p>Taxas adequadas de AGCC garantem a boa regula\u00e7\u00e3o do metabolismo <strong>\u00a0<\/strong>energ\u00e9tico, e modulam a resposta imune sist\u00eamica. Al\u00e9m disso, esses \u00e1cidos inibem a rea\u00e7\u00e3o inflamat\u00f3ria intestinal e recuperam a homeostase intestinal.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"Conclusao\"><\/span><strong>Conclus\u00e3o<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>De modo geral, a administra\u00e7\u00e3o de probi\u00f3ticos no c\u00e2ncer colorretal aliviou as complica\u00e7\u00f5es intestinais, protegou contra a disbiose induzida pela quimioterapia, e recuperou a produ\u00e7\u00e3o de \u00e1cidos graxos de cadeia curta. Sendo assim, este pode ser um tratamento promissor na pr\u00e1tica cl\u00ednica.<\/p>\n<p>Os autores sugerem que mais estudos sejam conduzidos para explicar os mecanismos de a\u00e7\u00e3o dos probi\u00f3ticos. Al\u00e9m disso, as melhores esp\u00e9cies probi\u00f3ticas, dose ideal e dura\u00e7\u00e3o da medi\u00e7\u00e3o devem ser definidas no futuro.<\/p>\n<ul>\n<li><a href=\"https:\/\/www.mdpi.com\/2072-6643\/15\/2\/356\" class=\"broken_link\"><strong>Clique aqui para ler o artigo completo.<\/strong><\/a><\/li>\n<\/ul>\n<p>Leia tamb\u00e9m:<\/p>\n<ul>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/como-o-uso-de-probioticos-pode-melhorar-o-desconforto-intestinal\/\">Como o uso de probi\u00f3ticos pode melhorar o desconforto intestinal?<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/consumo-de-carne-vermelha-e-processada-aumenta-risco-de-cancer-colorretal\/\">Consumo de carne vermelha e processada aumenta risco de c\u00e2ncer colorretal<\/a><\/li>\n<li><a href=\"https:\/\/nutritotal.com.br\/pro\/bacterias-cancer-de-prostata\/\">Bact\u00e9rias est\u00e3o associadas ao risco de c\u00e2ncer de pr\u00f3stata <\/a><\/li>\n<\/ul>\n<p><strong>Refer\u00eancia:<\/strong><\/p>\n<p>HUANG, Feng et al. <a href=\"https:\/\/www.mdpi.com\/article\/10.3390\/nu15020356\" class=\"broken_link\">Postoperative Probiotics Administration Attenuates Gastrointestinal Complications and Gut Microbiota Dysbiosis Caused by Chemotherapy in Colorectal Cancer Patients<\/a>. Nutrients, v. 15, n. 2, p. 356, 2023.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>O c\u00e2ncer colorretal \u00e9 um dos tumores malignos mais comuns na popula\u00e7\u00e3o mundial. Dentre as op\u00e7\u00f5es de tratamento, a quimioterapia pode trazer efeitos positivos. Por\u00e9m, as complica\u00e7\u00f5es tamb\u00e9m s\u00e3o comuns, tais como a disbiose intestinal, a diarreia e a dor abdominal. Neste sentido, seriam os probi\u00f3ticos uma op\u00e7\u00e3o eficaz para o tratamento auxiliar? Buscando responder [&hellip;]<\/p>\n","protected":false},"author":114981,"featured_media":57081,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2675,2959,1399],"tags":[147,3217,947,220,119,641],"divisao":[2185,3157,2193],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal<\/title>\n<meta name=\"description\" content=\"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal\" \/>\n<meta property=\"og:description\" content=\"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\" \/>\n<meta property=\"og:site_name\" content=\"Nutritotal PRO\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/nutritotalPRO\/\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/nutritotalPRO\/?ref=pages_you_manage&amp;_rdc=1&amp;_rdr\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-14T17:29:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-31T13:58:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png\" \/>\n\t<meta property=\"og:image:width\" content=\"580\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Reda\u00e7\u00e3o Nutritotal PRO\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Reda\u00e7\u00e3o Nutritotal PRO\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\"},\"author\":{\"name\":\"Reda\u00e7\u00e3o Nutritotal PRO\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/ebc724f6275a533739e9d1ad603f21a2\"},\"headline\":\"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal\",\"datePublished\":\"2023-02-14T17:29:56+00:00\",\"dateModified\":\"2023-05-31T13:58:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\"},\"wordCount\":699,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#organization\"},\"image\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png\",\"keywords\":[\"c\u00e2ncer\",\"c\u00e2ncer colorretal\",\"Microbiota intestinal\",\"oncologia\",\"probi\u00f3tico\",\"probi\u00f3ticos\"],\"articleSection\":[\"microbiota\",\"Nutri\u00e7\u00e3o Cl\u00ednica\",\"Probi\u00f3ticos\"],\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\",\"url\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\",\"name\":\"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal\",\"isPartOf\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png\",\"datePublished\":\"2023-02-14T17:29:56+00:00\",\"dateModified\":\"2023-05-31T13:58:11+00:00\",\"description\":\"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!\",\"breadcrumb\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage\",\"url\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png\",\"contentUrl\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png\",\"width\":580,\"height\":400,\"caption\":\"a\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nutritotal.com.br\/pro\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#website\",\"url\":\"https:\/\/nutritotal.com.br\/pro\/\",\"name\":\"Nutritotal PRO\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nutritotal.com.br\/pro\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#organization\",\"name\":\"Nutri Total\",\"url\":\"https:\/\/nutritotal.com.br\/pro\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/12\/Nutritotal-Pro-Vertical-02.png\",\"contentUrl\":\"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/12\/Nutritotal-Pro-Vertical-02.png\",\"width\":426,\"height\":426,\"caption\":\"Nutri Total\"},\"image\":{\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/nutritotalPRO\/\",\"https:\/\/www.instagram.com\/nutritotalpro\/\",\"https:\/\/www.youtube.com\/channel\/UCf01IyXkHLYUDGG0-XHR-YA\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/ebc724f6275a533739e9d1ad603f21a2\",\"name\":\"Reda\u00e7\u00e3o Nutritotal PRO\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/0b28a44567fd9e96213e21d1d40eeb15?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/0b28a44567fd9e96213e21d1d40eeb15?s=96&d=mm&r=g\",\"caption\":\"Reda\u00e7\u00e3o Nutritotal PRO\"},\"description\":\"A Reda\u00e7\u00e3o Nutritotal PRO \u00e9 formada por nutricionistas, m\u00e9dicos e estudantes de nutri\u00e7\u00e3o que t\u00eam a preocupa\u00e7\u00e3o de produzir conte\u00fados atuais, baseados em evid\u00eancia cient\u00edficas, sempre com o objetivo de facilitar a pr\u00e1tica cl\u00ednica de profissionais da \u00e1rea da sa\u00fade.\",\"sameAs\":[\"https:\/\/www.facebook.com\/nutritotalPRO\/?ref=pages_you_manage&_rdc=1&_rdr\",\"https:\/\/www.instagram.com\/nutritotalpro\/?utm_medium=copy_link\",\"https:\/\/www.linkedin.com\/company\/nutritotal-pro\/?viewAsMember=true\",\"https:\/\/www.youtube.com\/channel\/UCf01IyXkHLYUDGG0-XHR-YA\"],\"url\":\"https:\/\/nutritotal.com.br\/pro\/author\/nutritotal\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal","description":"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/","og_locale":"pt_BR","og_type":"article","og_title":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal","og_description":"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!","og_url":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/","og_site_name":"Nutritotal PRO","article_publisher":"https:\/\/www.facebook.com\/nutritotalPRO\/","article_author":"https:\/\/www.facebook.com\/nutritotalPRO\/?ref=pages_you_manage&_rdc=1&_rdr","article_published_time":"2023-02-14T17:29:56+00:00","article_modified_time":"2023-05-31T13:58:11+00:00","og_image":[{"width":580,"height":400,"url":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png","type":"image\/png"}],"author":"Reda\u00e7\u00e3o Nutritotal PRO","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Reda\u00e7\u00e3o Nutritotal PRO","Est. tempo de leitura":"3 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#article","isPartOf":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/"},"author":{"name":"Reda\u00e7\u00e3o Nutritotal PRO","@id":"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/ebc724f6275a533739e9d1ad603f21a2"},"headline":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal","datePublished":"2023-02-14T17:29:56+00:00","dateModified":"2023-05-31T13:58:11+00:00","mainEntityOfPage":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/"},"wordCount":699,"commentCount":0,"publisher":{"@id":"https:\/\/nutritotal.com.br\/pro\/#organization"},"image":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage"},"thumbnailUrl":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png","keywords":["c\u00e2ncer","c\u00e2ncer colorretal","Microbiota intestinal","oncologia","probi\u00f3tico","probi\u00f3ticos"],"articleSection":["microbiota","Nutri\u00e7\u00e3o Cl\u00ednica","Probi\u00f3ticos"],"inLanguage":"pt-BR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/","url":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/","name":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal","isPartOf":{"@id":"https:\/\/nutritotal.com.br\/pro\/#website"},"primaryImageOfPage":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage"},"image":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage"},"thumbnailUrl":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png","datePublished":"2023-02-14T17:29:56+00:00","dateModified":"2023-05-31T13:58:11+00:00","description":"Neste estudo com 100 pacientes de c\u00e2ncer colorretal, a administra\u00e7\u00e3o de probi\u00f3ticos reduziu as complica\u00e7\u00f5es gastrointestinais e protegou contra a disbiose. Confira os resultados completos!","breadcrumb":{"@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/"]}]},{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#primaryimage","url":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png","contentUrl":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2023\/02\/probioticos-e-cancer-colorretal-destacada.png","width":580,"height":400,"caption":"a\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais"},{"@type":"BreadcrumbList","@id":"https:\/\/nutritotal.com.br\/pro\/probioticos-e-cancer-colorretal\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nutritotal.com.br\/pro\/"},{"@type":"ListItem","position":2,"name":"A\u00e7\u00e3o dos probi\u00f3ticos nas complica\u00e7\u00f5es gastrointestinais em c\u00e2ncer colorretal"}]},{"@type":"WebSite","@id":"https:\/\/nutritotal.com.br\/pro\/#website","url":"https:\/\/nutritotal.com.br\/pro\/","name":"Nutritotal PRO","description":"","publisher":{"@id":"https:\/\/nutritotal.com.br\/pro\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nutritotal.com.br\/pro\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/nutritotal.com.br\/pro\/#organization","name":"Nutri Total","url":"https:\/\/nutritotal.com.br\/pro\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nutritotal.com.br\/pro\/#\/schema\/logo\/image\/","url":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/12\/Nutritotal-Pro-Vertical-02.png","contentUrl":"https:\/\/nutritotal.com.br\/pro\/wp-content\/uploads\/2022\/12\/Nutritotal-Pro-Vertical-02.png","width":426,"height":426,"caption":"Nutri Total"},"image":{"@id":"https:\/\/nutritotal.com.br\/pro\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/nutritotalPRO\/","https:\/\/www.instagram.com\/nutritotalpro\/","https:\/\/www.youtube.com\/channel\/UCf01IyXkHLYUDGG0-XHR-YA"]},{"@type":"Person","@id":"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/ebc724f6275a533739e9d1ad603f21a2","name":"Reda\u00e7\u00e3o Nutritotal PRO","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nutritotal.com.br\/pro\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/0b28a44567fd9e96213e21d1d40eeb15?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/0b28a44567fd9e96213e21d1d40eeb15?s=96&d=mm&r=g","caption":"Reda\u00e7\u00e3o Nutritotal PRO"},"description":"A Reda\u00e7\u00e3o Nutritotal PRO \u00e9 formada por nutricionistas, m\u00e9dicos e estudantes de nutri\u00e7\u00e3o que t\u00eam a preocupa\u00e7\u00e3o de produzir conte\u00fados atuais, baseados em evid\u00eancia cient\u00edficas, sempre com o objetivo de facilitar a pr\u00e1tica cl\u00ednica de profissionais da \u00e1rea da sa\u00fade.","sameAs":["https:\/\/www.facebook.com\/nutritotalPRO\/?ref=pages_you_manage&_rdc=1&_rdr","https:\/\/www.instagram.com\/nutritotalpro\/?utm_medium=copy_link","https:\/\/www.linkedin.com\/company\/nutritotal-pro\/?viewAsMember=true","https:\/\/www.youtube.com\/channel\/UCf01IyXkHLYUDGG0-XHR-YA"],"url":"https:\/\/nutritotal.com.br\/pro\/author\/nutritotal\/"}]}},"views":5299,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/posts\/57079"}],"collection":[{"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/users\/114981"}],"replies":[{"embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/comments?post=57079"}],"version-history":[{"count":2,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/posts\/57079\/revisions"}],"predecessor-version":[{"id":57083,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/posts\/57079\/revisions\/57083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/media\/57081"}],"wp:attachment":[{"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/media?parent=57079"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/categories?post=57079"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/tags?post=57079"},{"taxonomy":"divisao","embeddable":true,"href":"https:\/\/nutritotal.com.br\/pro\/wp-json\/wp\/v2\/divisao?post=57079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}